1. 悲伤；悲痛
Grief is a feeling of extreme sadness.
grief的反义词
e.g. ...a huge outpouring of national grief for the victims of the shootings...
举国上下对枪击事件中的遇害者所表现出的万分悲痛之情
e.g. Their grief soon gave way to anger.
他们的悲痛迅速转化为愤怒。
2. （事情）失败；（人）受挫，遭到不幸
If something comes to grief, it fails. If someone comes to grief, they fail in something they are doing, and may be hurt.
e.g. So many marriages have come to grief over lack of money...
许多婚姻都因缺钱而以失败告终。
e.g. He was driving a Mercedes racer at 100 mph and almost came to grief.
他当时驾驶着一辆梅塞德斯赛车以每小时100英里时速度飞驰，险些出事。
3. （表示惊奇或震惊）哎呀，天哪
Some people say 'Good grief' when they are surprised or shocked.
grief的近义词
e.g. 'He's been arrested for theft and burglary.' — 'Good grief!'
“他因为偷窃和入室盗窃而被逮捕了。”——“我的天哪！”